Characterization of binding affinity changes of SARS-CoV-2 omicron variant peptides to population-specific HLA
Abstract Background The evolution of SARS-CoV-2, particularly through new variants, presents significant global health challenges due to their potential for immune evasion and reduced vaccine effectiveness.This study aims to investigate the impact of mutations in the Spike protein of Omicron EG.5 and XBB.1.16 variants on the binding affinities of v